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Magnesium helps balance our hormones and without enough magnesium in the body, the cells and the various organs will start to weaken and eventually shut down notes MedlinePlus, a service of the National Institute of Health [2].Hormones are critical for our bodies in many ways: they facilitate growth and development, regulate mood and metabolism, and maintain sexual function. Magnesium plays a critical role in controlling the release of hormones. Magnesium is essential for the normal function of the parathyroid glands and metabolism of vitamin D. A study by Zofková et al of Institute of Endocrinology, Czech Republic associates deficiency of magnesium tohypoparathyroidism, low production of active vitamin D metabolites and vitamin D3 [1].

Impact of magnesium deficiency on hormones:

Magnesium and Parathyroid Hormone

Magnesium For Hormonal Balance

The parathyroid hormone (PTH) is responsible for maintaining calcium and phosphate levels in the body–two other nutrients that, along with Magnesium, play a vital role in keeping the body functioning normally. PTH is especially concerned with raising calcium levels in the blood.

When PTH levels are too high, however, the individual then suffers from hyperparathyroidism. The symptoms are slight and oftentimes unnoticeable: lethargy, depression, bone pain, low bone density levels, decreased sex drive and a general feeling of lousiness has been noted as some of the more prominent symptoms of hyperparathyroidism.

A review published in a 2006 issue of “Peritoneal Dialysis International” found that low magnesium levels corresponded with elevated parathyroid hormone levels. It successfully identified a link between magnesium levels and elevated parathyroid hormone levels, suggesting that magnesium plays a role in regulating parathyroid hormone levels. [3]

Magnesium and Insulin

Insulin is a hormone that regulates the body’s ability to metabolise fat and carbohydrates. It does this by removing excess glucose in the blood. Studies indicate low magnesium levels in patients suffering from diabetes compared to the general population. Magnesium deficiency is also known to raise insulin resistance; effectively making it more difficult for the body to absorb insulin.[4]

Five examples to show that Magnesium is key to proper functioning of hormones

Magnesium and Oestrogen

Magnesium For Hormonal BalanceOestrogen is primarily a female sex hormone. Studies have shown that oestrogen enhances the body’s absorption and utilisation of magnesium, possibly contributing to the long-held belief that women generally live longer than men. It develops the secondary sexual characteristics of a woman and regulates her menstrual cycle. This is, however, not the only function of oestrogen in the body. This particular hormone plays a significant role in preventing cardiovascular, bone and even mental disorders.

The problem, however, is that too much oestrogen saps the body’s reserve of magnesium. This is especially problematic when women are not getting enough magnesium in their body. Blood clots, kidney stones, gall stones, atherosclerosis, heel spurs and calcium deposits in breast cysts are just some of the problems faced by women with excess oestrogen but low magnesium levels.[5]

Migraines, eclampsia, pregnancy, menopause and premenstrual syndrome are also some conditions worsened when a woman does not have enough magnesium in her body.

Magnesium and Testosterone

Testosterone is the sex hormone that develops the secondary sexual characteristics of men (i.e. muscle mass and body hair). It also has positive effects on an individual’s libido irrespective of gender. This hormone also plays a prominent role in staving off osteoporosis. Since it builds up bone mass, men or women that do not produce enough testosterone often end up with severe bone problems. This is where magnesium comes into play once again – especially for older men.

Older men have higher sex hormone binding globulin (SHBG) levels in their bodies. This SHBG attracts testosterone. This is not immediately harmful to the body, but the testosterone drawn in by SHBG is prevented from reaching other parts of the body.

Magnesium, however, weakens the attractive properties of SGBG to testosterone–effectively freeing up the hormone and allowing it to be used where it is needed.[6]

Magnesium and 5-dehydroepiandrosterone DHEA

5-dehydroepiandrosterone (DHEA) is a hormone that plays an all-around role in the body. It affects strength, memory, physical performance, reproduction, cardiovascular health, diabetes prevention and longevity. [7]
DHEA is dangerous if directly introduced into the body via external sources. It is considered a steroid hormone with very little research being conducted on its long-term effects when artificially introduced into the body. People with low levels of DHEA have been noted to have low magnesium levels as well. Even increasing magnesium levels by 10% (and the resulting increase in DHEA levels as well) could knock down death by cardiovascular disease by 48% and any other kind of death by 36%.[8]

Reverse and Prevent Magnesium Deficiency

These are just five of the many hormones that the body produces on a regular basis and which need magnesium for proper functioning. If you have had a hormonal imbalance, chances are that you are deficient in Magnesium.

Fortunately, magnesium deficiency is easy to reverse. Enrich your diet with foods rich in Magnesium. You can additionally start taking oral or transdermal magnesium supplements like Magnesium Gel or Magnesium Rub.

While Mag365 is an effective and easily absorbed magnesium supplement, Essence Of Life Magnesium Rub is a good way to deliver high levels of magnesium directly through the skin to your cells. It is advised particularly if you are sensitive to oral intake of magnesium.


  1. The relationship between magnesium and calciotropic hormones.
  2. MedlinePlus; Hormones; May 2011
  3. Peritoneal Dialysis International"; Relationship Between Serum Magnesium, Parathyroid Hormone, and Vascular Calcification in Patients on Dialysis: A Literature Review; Wei M, et al.; May 2006
  4. Magnesium Deficiency Is Associated With Insulin Resistance in Obese Children.
  5., “Magnesium, Estrogen and Vitamin D”, accessed 2011-10-05. URL:
  6. "Journal of the American College of Nutrition"; Skeletal and Hormonal Effects of Magnesium Deficiency; Rude RK, et al.; April 2009
  7. “DHEA: Ignore the Hype”,
  8. “Soak Your Way to Health! DHEA; Magnesium and the Fountain of Youth”.

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